MEDICAL PROFESSIONALS
Disease State
- Afib is the most common cardiac arrhythmia in clinical practice
- The impact of Afib
- Pathophysiology of Afib
- Increased understanding of the pathophysiology of Afib guiding new treatment approaches.
Increased understanding of the pathophysiology of Afib guiding new treatment approaches
Factors responsible for the onset of Afib include triggers that induce the arrhythmia and the substrate that sustains it [reviewed in (ref. 13)]. While pharmacological approaches attempt to control cardiac rate or rhythm, they do not directly address the source of the arrhythmia and thus may have only limited efficacy in preventing recurrence. In this regard, newer therapeutic approaches such as catheter ablation focus directly on the elimination of ectopic sources and reentrant pathways. Understanding more about these aberrant foci and pathways will allow for more effective ablative approaches.
Figure: ectopic foci and single/multiple circuit re-entries with ablation lesions.
AFIB alliance members
